HMOX2 antibody

Catalog No. ABIN155125

Product Details anti-HMOX2 Antibody

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Reactivity: Human, Mouse, Rat, Monkey, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMOX2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: The antibody recognizes ~36 kDa Heme-Oxygenase-2.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide surrounding amino acid 25 of human HO-2

Application Details

Application Notes: Western Blot: 1-4 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry on frozen sections: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for HMOX2

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Alternative Name: Heme Oxygenase 2 (HMOX2) (HMOX2 Products)

Synonyms: HO-2 antibody, HO2 antibody, HMOX2 antibody, Ho-2 antibody, im:6909100 antibody, si:dkey-44g23.7 antibody, AtHO2 antibody, T9J22.22 antibody, T9J22_22 antibody, heme oxygenase 2 antibody, hmox2 antibody, ho-2 antibody, heme oxygenase 2 antibody, Heme oxygenase 2 antibody, heme oxygenase 2, putative antibody, heme oxygenase 2a antibody, heme oxygenase 2 L homeolog antibody, HMOX2 antibody, Hmox2 antibody, HO2 antibody, ho2 antibody, CNF01200 antibody, CPR_0203 antibody, CGB_F5120W antibody, hmox2a antibody, hmox2.L antibody

Background: Heme oxygenase (HO) is a microsomal enzyme that oxidatively cleaves heme, a pro-oxidant, into carbon monoxide and biliverdin. Two heme oxygenase isozymes, termed HO-1 and HO-2, have been identified so far. At the amino acid level, HO-1 and HO-2 are 42 % homologous. However, each isozyme is evolutionary highly conserved. HO-1 is the inducible form of the enzyme and is therefore also referred to as stress protein Hsp32. Expression of HO-1 can be induced by a variety of stimuli such as heme, metals, hormones, UV radiation and sulfhydryl depleting agents. In contrast, HO-2 is the constituitive form of the enzyme. It is not inducible by exogeneous stimuli and HO-2 is the most prevalent form in most tissues, except the spleen where HO-1 levels are predominant under normal conditions.Synonyms: HO-2, HO2

Gene ID: 3163

NCBI Accession: NP_001120676

UniProt: P30519

Pathways: Transition Metal Ion Homeostasis