Western blotting (0.5-4 μg/mL). Jurkat cell lysate, mouse small intestine tissue lysate and rat kidney can be used asPositive Controls. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
SLC5A2 antibody, slc5a2 antibody, DKFZp469E0433 antibody, zgc:85792 antibody, MGC83377 antibody, SGLT2 antibody, Sglt2 antibody, solute carrier family 5 member 2 antibody, solute carrier family 5 (sodium/glucose cotransporter), member 2 antibody, solute carrier family 5 (sodium/glucose cotransporter), member 2 L homeolog antibody, SLC5A2 antibody, slc5a2 antibody, slc5a2.L antibody, Slc5a2 antibody
Background
Sodium glucose co transporters (SGLTs) are located in the brush-border membrane, but transported out of the cell across the basolateral membranes by a facilitated sugar transporter (GLUT). At least three members of SGLTs (SGLT 1-3) have been cloned and characterized. SGLTs transport a methyl-D-glucoside (a-MDG), a non-metabolized model substrate, in Na-dependent manner. SGLT-1 does not discriminate a-MDG, glucose, and galactose. SGLT2/3 do not transport D-galactose efficiently.Synonyms: Low affinity sodium-glucose cotransporter, Na(+)/glucose cotransporter 2, Sodium/glucose cotransporter 2, Solute carrier family 5 member 2