CD59 antibody
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- Target See all CD59 Antibodies
- CD59
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD59 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- Human CD59
- Purification
- Purified from ascitic fluid via Protein G Chromatography
- Clone
- 1F5
- Isotype
- IgG1
- Top Product
- Discover our top product CD59 Primary Antibody
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- Application Notes
- This product is suitable for use in flow cytometry.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/ml
- Buffer
- Purified Ig buffered in PBS and 0.02% NaN . (Purified from ascitic fluid via Protein G Chromatography).
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- CD59
- Alternative Name
- CD59 (CD59 Products)
- Synonyms
- 16.3A5 antibody, 1F5 antibody, EJ16 antibody, EJ30 antibody, EL32 antibody, G344 antibody, HRF-20 antibody, HRF20 antibody, MAC-IP antibody, MACIF antibody, MEM43 antibody, MIC11 antibody, MIN1 antibody, MIN2 antibody, MIN3 antibody, MIRL antibody, MSK21 antibody, p18-20 antibody, Cd59a antibody, Cd59b antibody, MACIP antibody, CD59 molecule (CD59 blood group) antibody, CD59 molecule antibody, CD59 antibody, Cd59 antibody
- Background
- CD59 (also known as HRF20, protectin) is a 20 kDa glycoprotein attached to the plasma membrane by a glycosylphosphatidylinositol (GPI) anchor. It blocks MAC formation in the complement pathway by interfering with C9 membrane insertion and polymerization, but it does not affect the generation of C3 and C5 activation products. CD59 is expressed on several cell types, including leukocytes, endothelial and epithelial cells, erythrocytes, and cells of the central nervous system. CD59 belongs to the Ly6 superfamily of proteins. This product is suitable for use in flow cytometry.
- Pathways
- Complement System
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