Platelet antibody
Reactivity: Mouse
FACS
Host: Rat
Monoclonal
AIP21
unconjugated
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- Target
- Platelet
- Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
-
Conjugate
- Un-conjugated
- Application
- Flow Cytometry (FACS)
- Specificity
- Mouse Platelets
- Purification
- Purified
- Clone
- AIP21
- Isotype
- IgG2a
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-
- Application Notes
- This antibody is suitable for use in flow cytometry and functional assays.
- Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/ml
- Buffer
- Purified IgM buffered in PBS and 0.02% NaN
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
-
- Target
- Platelet
- Background
- Anti-mouse platelet monoclonal antibody (clone AIP21) detects an unidentified antigen on mouse platelets that is not identical to CD9, GPIV or integrins. This antigen is also present on B16F10 and KN-3 cells, but not thymocytes or splenocytes. This antibody induces mouse platelet aggregation in the absence of plasma components via an FcR-independent mechanism. A dramatic increase in tyrosine phosphorylation of the 52 kDa Shc protein was observed during AIP21-mediated platelet aggregation. This antibody is suitable for use in flow cytometry and functional assays.
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