AIM2 antibody (AA 1-260)

Catalog No. ABIN1678616

The Rabbit Polyclonal anti-AIM2 antibody is suitable to detect AIM2 in samples from Human. It has been validated for WB and IF.

Quick Overview for AIM2 antibody (AA 1-260) (ABIN1678616)

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AIM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-AIM2 Antibody

Binding Specificity: AA 1-260

Sequence: MESKYKEILL LTGLDNITDE ELDRFKFFLS DEFNIATGKL HTANRIQVAT LMIQNAGAVS AVMKTIRIFQ KLNYMLLAKR LQEEKEKVDK QYKSVTKPKP LSQAEMSPAA SAAIRNDVAK QRAAPKVSPH VKPEQKQMVA QQESIREGFQ KRCLPVMVLK AKKPFTFETQ EGKQEMFHAT VATEKEFFFV KVFNTLLKDK FIPKRIIIIA RYYRHSGFLE VNSASRVLDA ESDQKVNVPL NIIRKAGETP KINTLQTQPL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human AIM2 (NP_004824.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AIM2

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Alternative Name: AIM2

Background: AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.,AIM2,PYHIN4,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,AIM2

Molecular Weight: 38 kDa

Gene ID: 9447

UniProt: O14862

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome