PZP antibody (AA 620-740)

Catalog No. ABIN6220213

Product Details anti-PZP Antibody

Target: PZP (Pregnancy Zone Protein (PZP))

Binding Specificity: AA 620-740

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PZP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VKDLTNFPDN VDQQEEEQGH CPRPFFIHNG AIYVPLSSNE ADIYSFLKGM GLKVFTNSKI RKPKSCSVIP SVSAGAVGQG YYGAGLGVVE RPYVPQLGTY NVIPLNNEQS SGPVPETVRS Y

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 620-740 of human PZP (NP_002855.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PZP

Target: PZP (Pregnancy Zone Protein (PZP))

Alternative Name: PZP (PZP Products)

Synonyms: A1m antibody, pregnancy zone protein antibody, pregnancy-zone protein antibody, CpipJ_CPIJ000348 antibody, Pzp antibody, PZP antibody

Background: The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients.,PZP,CPAMD6,Cell Biology & Developmental Biology,Cell Adhesion,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,Cell Type Marker,Neuron marker,Synapse marker,PZP

Molecular Weight: 140 kDa/163 kDa

Gene ID: 5858

UniProt: P20742