NLRP12 antibody (Internal Region)

Catalog No. ABIN1686781

This Goat Polyclonal antibody specifically detects NLRP12 in WB and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for NLRP12 antibody (Internal Region) (ABIN1686781)

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Reactivity: Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This NLRP12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-NLRP12 Antibody

Binding Specificity: Internal Region

Purpose: Nalp12 / Nlrp12 (rodent)

Sequence: KPGTPTFKVP ANQR

Cross-Reactivity: Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 100 kDa band observed in Mouse Liver and Spleen lysates (calculated MW of 119 kDa according to NP_001028603.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Jéru et al, Proc Nat

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for NLRP12

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Alternative Name: Nlrp12

Background: Nlrp12, NLR family, pyrin domain containing 12, Nalp12, PYPAF7, NACHT, LRR and PYD containing protein 12, NACHT, LRR and PYD domains-containing protein 12, PYRIN-containing APAF1-like protein 7, monarch-1

Molecular Weight: 100 kDa

Gene ID: 378425, 292541

NCBI Accession: NP_001028603

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome