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CUTC antibody (AA 201-273) (AbBy Fluor® 350)

CUTC Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 350
Catalog No. ABIN1692987
  • Target See all CUTC Antibodies
    CUTC (CutC Copper Transporter Homolog (CUTC))
    Binding Specificity
    • 14
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    AA 201-273
    Reactivity
    • 42
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 40
    • 2
    Rabbit
    Clonality
    • 42
    Polyclonal
    Conjugate
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CUTC antibody is conjugated to AbBy Fluor® 350
    Application
    • 37
    • 20
    • 12
    • 12
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CUTC
    Isotype
    IgG
    Top Product
    Discover our top product CUTC Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CUTC (CutC Copper Transporter Homolog (CUTC))
    Alternative Name
    CUTC (CUTC Products)
    Synonyms
    zgc:103406 antibody, RP11-483F11.3 antibody, 2310039I18Rik antibody, AI326282 antibody, CGI-32 antibody, cutC copper transporter antibody, cutC copper transporter homolog (E. coli) antibody, CUTC antibody, cutc antibody, Cutc antibody
    Background

    Synonyms: CGI 32, CGI32, Copper homeostasis protein cutC homolog, cutC, CutC copper transporter homolog E. coli, CUTC_HUMAN, RP11-483F11.3.

    Background: Copper is an essential micronutrient used as a co-factor for several essential enzymes in all living organisms. Due to the high toxicity of copper, its metabolism is tightly regulated and defects in this regulation can cause Menkes (deficiency) or Wilson (accumulation) disease in various tissue. CUTC (cutC copper transporter homolog (E. coli)), also known as CGI-32, is a 273 amino acid protein belonging to the cutC family. CUTC is involved in copper homeostasis and is encoded by a gene located on human chromosome 10, which contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10.

    Gene ID
    51076
    Pathways
    Transition Metal Ion Homeostasis
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