NCMAP antibody (Noncompact Myelin Associated Protein) (Alexa Fluor 647)

Details for Product anti-NCMAP Antibody No. ABIN1699360
Antigen
  • C1orf130
  • MP11
  • A330049M08Rik
  • AA545175
  • Mp11
  • non-compact myelin associated protein
  • noncompact myelin associated protein
  • NCMAP
  • Ncmap
Reactivity
Human, Mouse (Murine), Rat (Rattus)
19
14
14
Host
Rabbit
19
Clonality
Polyclonal
Conjugate
This NCMAP antibody is conjugated to Alexa Fluor 647
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
12
4
4
3
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human C1orf130
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others NCMAP products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name C1orf130
Background

Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf130 gene product has been provisionally designated C1orf130 pending further characterization.

Subcellular location: Extracellular

Synonyms: C1orf130, CA130_HUMAN, Uncharacterized protein C1orf130.

Gene ID 400746
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months
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