Tec Protein Tyrosine Kinase (TEC) (AA 11-100) antibody (Biotin)

Catalog No. ABIN1700413

This Rabbit Polyclonal antibody specifically detects Tec Protein Tyrosine Kinase in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for Tec Protein Tyrosine Kinase (TEC) (AA 11-100) antibody (Biotin) (ABIN1700413)

Target: Tec Protein Tyrosine Kinase (TEC)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details

Binding Specificity: AA 11-100

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TEC/Tec protein tyrosine kinase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details

Target: Tec Protein Tyrosine Kinase (TEC)

Alternative Name: TEC

Background:

Synonyms: MGC126760, MGC126762, PSCTK4, Tec, Tec protein tyrosine kinase, TEC_HUMAN, Tec protein tyrosine kinase, Tyrosine protein kinase, Tyrosine-protein kinase Tec.

Background: TEC is a belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

Gene ID: 7006

Pathways: Fc-epsilon Receptor Signaling Pathway