Protein C Light Chain (AA 131-230) antibody (Biotin)
-
- Target
- Protein C Light Chain
- Binding Specificity
- AA 131-230
- Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- Biotin
-
Application
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Vitamin K-dependent protein C light chain
- Isotype
- IgG
-
-
- Application Notes
-
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
-
- Target
- Protein C Light Chain
- Background
-
Synonyms: Protein C, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, EC 3.4.21.69, PC, PROC, PROC1, Vitamin K dependent protein C precursor, APC, EC 3.4.21.69, PC, proC, PROC_HUMAN, Protein C inactivator of coagulation factors Va and VIIIa, Vitamin K dependent protein C, Vitamin K-dependent protein C, Vitamin K-dependent protein C light chain.
Background: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009].
-
