CTNND1 antibody (pTyr228) (Cy5)

Catalog No. ABIN1704077

Product Details anti-CTNND1 Antibody (Cy5)

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Binding Specificity: pTyr228

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTNND1 antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human delta 1 Catenin around the phosphorylation site of Tyr228

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CTNND1

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Abstract: CTNND1 Products

Synonyms: CAS antibody, CTNND antibody, P120CAS antibody, P120CTN antibody, p120 antibody, p120(CAS) antibody, p120(CTN) antibody, Catns antibody, cas antibody, Xp120 antibody, ctnnd antibody, p120cas antibody, p120ctn antibody, p120(ctn) antibody, Xp120(ctn) antibody, p120-catenin antibody, CTNND1 antibody, AA409437 antibody, AU019353 antibody, Ctnnd antibody, P120 antibody, mKIAA0384 antibody, catenin delta 1 antibody, catenin (cadherin-associated protein), delta 1 antibody, catenin (cadherin associated protein), delta 1 antibody, catenin delta 1 L homeolog antibody, CTNND1 antibody, Ctnnd1 antibody, ctnnd1 antibody, ctnnd1.L antibody

Background:

Synonyms: delta 1 Catenin phospho Y228, p-delta 1 Catenin phospho Y228, Cadherin associated Src substrate, Cadherin-associated Src substrate, CAS, Catenin cadherin associated protein delta 1, Catenin delta 1, Catenin delta-1, CTND1_HUMAN, CTNND 1, CTNND, CTNND1, KIAA0384, p120, P120 CAS, p120 catenin, P120 CTN, p120Cas, p120Ctn, P120CAS, P120CTN.

Background: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

Gene ID: 1500

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling