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FAK antibody (pTyr576) (Cy5)

PTK2 Reactivity: Mouse WB, IF (p), IF (cc) Host: Rabbit Polyclonal Cy5

Catalog No. ABIN1704203

Datasheet as PDF

Target See all FAK (PTK2) Antibodies

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
Binding Specificity
43

33

30

28

23

22

22

18

16

16

13

11

7

5

5

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
pTyr576
Reactivity
327

274

205

21

21

17

16

11

8

6

6

4

3

3

2

1

1

1

1

1
Mouse
Host
336

15

3

2

1

1
Rabbit
Compatible Secondaries
Clonality
330

28
Polyclonal
Conjugate
156

17

16

12

10

10

10

10

10

10

10

10

10

10

10

9

6

6

6

6

6

6

1

1
This FAK antibody is conjugated to Cy5
Application
290

133

133

120

106

68

60

42

31

28

23

5

2

2
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity

Mouse

Predicted Reactivity

Human,Rat,Dog,Cow,Horse,Chicken,Rabbit

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic phosphopeptide derived from human PTK2 around the phosphorylation site of Tyr576

Isotype

IgG

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anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr576) antibody
PTK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

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PTK2 Reactivity: Human WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB20775 unconjugated

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PTK2 Reactivity: Human WB, ELISA, IP, PLA Host: Mouse Monoclonal 2C3 unconjugated

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PTK2 Reactivity: Human WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB20776 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr861) antibody
PTK2 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody
PTK2 Reactivity: Human WB, ELISA, IHC, ICC Host: Mouse Monoclonal 10H7 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody
PTK2 Reactivity: Human ELISA, FACS, ICC Host: Mouse Monoclonal 10H7E9 unconjugated

Application Notes

IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date

12 months
Target

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Alternative Name

FAK (PTK2 Products)

Background

Synonyms: FAK phospho Y576, p-FAK phospho Y576, FADK 1, FADK, FAK 1, FAK related non kinase polypeptide, FAK1, Focal adhesion kinase 1, FRNK, pp125FAK, Protein tyrosine kinase 2, Protein Tyrosine Kinase Cytoplasmic, PTK 2, FAK1_HUMAN, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK.
Background: Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR LOCATION] Cell junction, focal adhesion. Cell membrane, Peripheral membrane protein, Cytoplasmic side. Note=Constituent of focal adhesions.

Gene ID

5747

Pathways

Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling