CYP26A1 antibody (AA 101-200) (Cy5)
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- Target See all CYP26A1 Antibodies
- CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))
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Binding Specificity
- AA 101-200
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYP26A1 antibody is conjugated to Cy5
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CYP26A1
- Isotype
- IgG
- Top Product
- Discover our top product CYP26A1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))
- Alternative Name
- CYP26A1 (CYP26A1 Products)
- Synonyms
- CP26 antibody, CYP26 antibody, P450RAI antibody, P450RAI1 antibody, Cyp26 antibody, P450RA antibody, RAH antibody, RACE antibody, XCYP26A1 antibody, cyp26 antibody, xCYP26 antibody, cp26 antibody, p450rai antibody, p450rai1 antibody, CYP26A antibody, cb24 antibody, id:ibd5061 antibody, wu:fb81e05 antibody, cytochrome P450 family 26 subfamily A member 1 antibody, cytochrome P450, family 26, subfamily a, polypeptide 1 antibody, cytochrome P450 family 26 subfamily A member 1 S homeolog antibody, cytochrome P450 family 26 subfamily A member 1 L homeolog antibody, cytochrome P450, family 26, subfamily A, polypeptide 1 antibody, CYP26A1 antibody, Cyp26a1 antibody, cyp26a1.S antibody, cyp26a1.L antibody, cyp26a1 antibody
- Background
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Synonyms: CP26, CP26A_HUMAN, CYP26, CYP26A 1, cyp26a1, Cytochrome P450 26A1, Cytochrome P450 family 26 subfamily A polypeptide 1, Cytochrome P450 retinoic acid-inactivating 1, cytochrome P450, family 26, subfamily A, polypeptide 1, cytochrome P450, subfamily XXVIA, polypeptide 1, Cytochrome P450RAI, hP450RAI, OTTHUMP00000020102, OTTHUMP00000020103, P450, P450 retinoic acid inactivating 1, P450RAI, P450RAI1, Retinoic acid 4 hydroxylase, Retinoic acid 4-hydroxylase, Retinoic acid metabolizing cytochrome, Retinoic acid-metabolizing cytochrome.
Background: The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1 is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor 2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos.
- Gene ID
- 1592
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Monocarboxylic Acid Catabolic Process
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