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PRAM1 antibody (AA 551-650) (Cy5.5)

PRAM1 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Cy5.5
Catalog No. ABIN1705817
  • Target See all PRAM1 Antibodies
    PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))
    Binding Specificity
    • 14
    • 2
    • 1
    • 1
    AA 551-650
    Reactivity
    • 19
    • 1
    Human
    Host
    • 17
    • 1
    • 1
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRAM1 antibody is conjugated to Cy5.5
    Application
    • 12
    • 12
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PRAM1
    Isotype
    IgG
    Top Product
    Discover our top product PRAM1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))
    Alternative Name
    PRAM1 (PRAM1 Products)
    Synonyms
    PRAM1 antibody, AY665714 antibody, PML-RAR antibody, PRAM-1 antibody, RGD1564330 antibody, PML-RARA regulated adaptor molecule 1 antibody, PML-RAR alpha-regulated adaptor molecule 1 antibody, PRAM1 antibody, Pram1 antibody
    Background

    Synonyms: PML RAR, PML RARA regulated adaptor molecule 1, PML RARA target gene encoding an Adaptor Molecule 1, PML-RARA-regulated adapter molecule 1, PRAM 1, PRAM, PRAM-1, PRAM_HUMAN, PRAM1.

    Background: Complete remission of acute promyelocytic leukemia can be achieved by treating patients with retinoic acid, and PML-RAR-a (promyelocytic leukemia-retinoic acid receptor alpha fusion protein) plays a major role in mediating retinoic acid effects in leukemia cells. The retinoic acid-induced gene, PRAM-1 (PML-RAR-a target gene encoding an adaptor molecule 1) encodes an adaptor protein which is expressed and modulated during normal human myelopoiesis. PRAM-1 expression is hindered by expression of PML-RAR-a. The 718 amino acid PRAM-1 protein contains eight N-terminal proline-rich repeats and several proline residues that are clustered as type I or type II SH3 recognition motifs. PRAM-1 demonstrates expression in hematopoietic tissues and lung.

    Pathways
    Regulation of Leukocyte Mediated Immunity
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