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PBX3 antibody (AA 65-130) (Cy7)

PBX3 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal Cy7
Catalog No. ABIN1708110
  • Target See all PBX3 Antibodies
    PBX3 (Pre-B-Cell Leukemia Transcription Factor 3 (PBX3))
    Binding Specificity
    • 14
    • 13
    • 9
    • 1
    • 1
    • 1
    AA 65-130
    Reactivity
    • 35
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 33
    • 2
    Rabbit
    Clonality
    • 33
    • 2
    Polyclonal
    Conjugate
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PBX3 antibody is conjugated to Cy7
    Application
    • 34
    • 19
    • 12
    • 12
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PBX3
    Isotype
    IgG
    Top Product
    Discover our top product PBX3 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PBX3 (Pre-B-Cell Leukemia Transcription Factor 3 (PBX3))
    Alternative Name
    PBX3 (PBX3 Products)
    Synonyms
    Pbx3b antibody, pre B cell leukemia homeobox 3 antibody, PBX homeobox 3 antibody, Pbx3 antibody, PBX3 antibody
    Background

    Synonyms: Homeobox protein PBX3, MGC134053, OTTHUMP00000064213, Pbx 3, Pbx3, PBX3_HUMAN, Pre B cell leukemia homeobox 3, Pre B cell leukemia transcription factor 3, Pre-B-cell leukemia transcription factor 3, RP11 336P12.1.

    Background: Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1,19)(q23,p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92 % and 94 % respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.

    Gene ID
    5090
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