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FAK antibody (pSer910) (FITC)

PTK2 Reactivity: Mouse, Rat, Xenopus laevis WB, IF (p), IF (cc) Host: Rabbit Polyclonal FITC

Catalog No. ABIN1709684

Datasheet as PDF

Target See all FAK (PTK2) Antibodies

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
Binding Specificity
43

33

30

28

23

22

22

17

16

16

13

11

7

5

5

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
pSer910
Reactivity
327

273

204

21

20

17

16

11

8

6

6

4

3

3

2

1

1

1

1

1
Mouse, Rat, Xenopus laevis
Host
335

15

3

2

1

1
Rabbit
Compatible Secondaries
Clonality
329

28
Polyclonal
Conjugate
156

17

15

12

10

10

10

10

10

10

10

10

10

10

10

9

6

6

6

6

6

6

1

1
This FAK antibody is conjugated to FITC
Application
289

132

132

120

106

68

60

42

31

28

23

5

2

2
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity

Mouse, Rat, Xenopus laevis

Predicted Reactivity

Human,Chicken

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic phosphopeptide derived from human PTK2 around the phosphorylation site of Tyr910

Isotype

IgG

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PTK2 Reactivity: Human WB, ELISA, IP, PLA Host: Mouse Monoclonal 2C3 unconjugated

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PTK2 Reactivity: Human WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB20776 unconjugated

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PTK2 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody
PTK2 Reactivity: Human WB, ELISA, IHC, ICC Host: Mouse Monoclonal 10H7 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody
PTK2 Reactivity: Human ELISA, FACS, ICC Host: Mouse Monoclonal 10H7E9 unconjugated

Application Notes

IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date

12 months
Target

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Alternative Name

FAK (PTK2 Products)

Background

Synonyms: FAK phospho S910, p-FAK phospho S910, FADK 1, FADK, FAK 1, FAK related non kinase polypeptide, FAK1, Focal adhesion kinase 1, FRNK, pp125FAK, Protein tyrosine kinase 2, Protein Tyrosine Kinase Cytoplasmic, PTK 2, FAK1_HUMAN, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK.
Background: Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

Gene ID

5747

Pathways

Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling