GSTT2 antibody (AA 11-100) (HRP)

Catalog No. ABIN1711350

Product Details anti-GSTT2 Antibody (HRP)

Target: GSTT2 (Glutathione S-Transferase theta 2 (GSTT2))

Binding Specificity: AA 11-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTT2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GSTT2/Glutathione S Transferase ta 2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GSTT2

Target: GSTT2 (Glutathione S-Transferase theta 2 (GSTT2))

Alternative Name: GSTT2 (GSTT2 Products)

Synonyms: GSTT2 antibody, AI266894 antibody, Yrs antibody, mGSTT2 antibody, GSTT2B antibody, GSTT3 antibody, glutathione S-transferase theta-2B antibody, glutathione S-transferase, theta 2 antibody, glutathione S-transferase theta-2 antibody, glutathione S-transferase theta 2 (gene/pseudogene) antibody, glutathione S-transferase theta 2 antibody, LOC706634 antibody, Gstt2 antibody, CpipJ_CPIJ002679 antibody, LOC100338449 antibody, GSTT2 antibody, LOC100717041 antibody

Background:

Synonyms: Glutathione S Transferase theta 2, EC 2.5.1.18, Glutathione S transferase 12, Glutathione S transferase Yrs Yrs, Glutathione S-transferase theta-2, Glutathione S-transferase theta-2B, GST 12 12, GST class theta 2, GST class-theta-2, GST T2, GSTT 2, GSTT2, GSTT2 protein, GSTT2_HUMAN, GSTT2B, MGC182032, OTTHUMP00000198491, OTTHUMP00000198492.

Background: Glutathione (GSH) is a tripeptide antioxidant which reduces disulfide bonds between cytoplasmic proteins. The constitutive enzyme glutathione reductase transforms glutathione into its reduced state which ultimately can provide a measure of cellular toxicity. GSTT2 (glutathione S-transferase theta-2), also known as GST class-theta-2, is a 244 amino acid enzyme with sulfatase activity that functions in conjugating reduced glutathione to hydrophobic electrophiles. GSTT2 exists as a homodimer in the cytoplasm and is expressed in low levels in the liver and the lung. GSTT2 belongs to the GST superfamily and contains both a GST C-terminal and a GST N-terminal domain. The gene encoding GSTT2 exists on human chromosome 22.

Gene ID: 2953

Pathways: Myometrial Relaxation and Contraction, Autophagy