TUBGCP4 antibody (AA 101-200) (HRP)

Catalog No. ABIN1712310

Product Details anti-TUBGCP4 Antibody (HRP)

Target: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Binding Specificity: AA 101-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBGCP4 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GCP4

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TUBGCP4

Target: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Alternative Name: GCP4 (TUBGCP4 Products)

Synonyms: RGD1306924 antibody, 76p antibody, MGC81229 antibody, zgc:194561 antibody, zgc:194580 antibody, DKFZp459O2210 antibody, 76P antibody, GCP-4 antibody, GCP4 antibody, h76p antibody, hGCP4 antibody, hGrip76 antibody, 4932441P04Rik antibody, D2Ertd435e antibody, tubulin, gamma complex associated protein 4 antibody, tubulin gamma complex associated protein 4 antibody, tubulin gamma complex associated protein 4 L homeolog antibody, Tubgcp4 antibody, TUBGCP4 antibody, tubgcp4.L antibody, tubgcp4 antibody

Background:

Synonyms: 76P, FLJ14797, Gamma tubulin complex component 4, Gamma tubulin ring complex protein 76p gene, Gamma tubulin ring complex protein, GCP 4, GCP4, h76p, hGCP4, Hgrip76, TUBGCP 4, TUBGCP4, Tubulin gamma complex associated protein 4, GCP4_HUMAN.

Background: The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complex-associated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP4 (gamma-tubulin complex component 4), also known as TUBGCP4, is a ubiquitously expressed 667 amino acid member of the gamma-Tubulin complex that localizes to the metaphase spindle during mitosis. In response to proteosome inhibition, GCP4 exhibits increased accumulation at the pericentiolar material where it participates in microtubule organization and nucleation.

Gene ID: 27229

Pathways: M Phase