GABRP antibody (AA 81-180) (HRP)

Catalog No. ABIN1712528

Product Details anti-GABRP Antibody (HRP)

Target: GABRP (gamma-aminobutyric Acid (GABA) A Receptor, pi (GABRP))

Binding Specificity: AA 81-180

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRP antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GABRP/GABA A receptor pi

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GABRP

Target: GABRP (gamma-aminobutyric Acid (GABA) A Receptor, pi (GABRP))

Alternative Name: GABRP/GABA A receptor pi (GABRP Products)

Synonyms: gamma-aminobutyric acid type A receptor pi subunit antibody, gamma-aminobutyric acid (GABA) A receptor, pi antibody, Gabrp antibody, GABRP antibody

Background:

Synonyms: GABAA receptor, GABAA receptor subunit pi, GABRP, Gamma aminobutyric acid GABA A receptor pi, Gamma aminobutyric acid A receptor pi, Gamma aminobutyric acid receptor pi subunit, Gamma aminobutyric acid receptor subunit pi, Gamma-aminobutyric acid receptor subunit pi, GBRP_HUMAN, MGC126386, MGC126387.

Background: GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.

Gene ID: 2568