NFATC4 antibody (pSer168, pSer170)

Catalog No. ABIN1713679

Product Details anti-NFATC4 Antibody

Target: NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))

Binding Specificity: pSer168, pSer170

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFATC4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human NFATC4 around the phosphorylation site of Ser168 + Ser170

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for NFATC4

Target: NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))

Alternative Name: NFATC4 (NFATC4 Products)

Synonyms: si:dkeyp-66d1.4 antibody, NFATC4 antibody, 3110041H08Rik antibody, AW107667 antibody, AW546455 antibody, Nfat3 antibody, NF-ATc4 antibody, NFAT3 antibody, nuclear factor of activated T-cells 4 antibody, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 antibody, NFATC4 antibody, nfatc4 antibody, Nfatc4 antibody

Background:

Synonyms: NFATC4 phospho S168 + S170, p-NFATC4 phospho S168 + S170, NFATC4 cytoplasmic 4, NF ATc4, NF-AT3, NF-ATc4, NFAC4_HUMAN, NFAT3, NFATc4, Nuclear factor of activated T cells cytoplasmic 4, Nuclear factor of activated T cells cytoplasmic calcineurin dependent 4, Nuclear factor of activated T-cells, nuclear factor of activated T-cells cytoplasmic 4, Nuclear factor of activated T-cells cytoplasmic calcineurin-dependent 4, T cell transcription factor NFAT3, T-cell transcription factor NFAT3.

Background: The product of this gene is a member of the nuclearfactors of activated T cells DNA-binding transcription complex.This complex consists of at least two components: a preexistingcytosolic component that translocates to the nucleus upon T cellreceptor (TCR) stimulation and an inducible nuclear component.Other members of this family of nuclear factors of activated Tcells also participate in the formation of this complex. Theproduct of this gene plays a role in the inducible expression ofcytokine genes in T cells, especially in the induction of the IL-2and IL-4. Alternatively spliced transcript variants encodingdifferent isoforms have been noted for this gene. [provided byRefSeq, Oct 2008].

Gene ID: 4776

Pathways: RTK Signaling, WNT Signaling