Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

GCAP1 antibody (AA 51-150)

GUCA1A Reactivity: Mouse, Rat ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1714544
  • Target See all GCAP1 (GUCA1A) Antibodies
    GCAP1 (GUCA1A) (Guanylate Cyclase Activator 1A (Retina) (GUCA1A))
    Binding Specificity
    • 14
    • 9
    • 5
    • 4
    • 1
    • 1
    • 1
    AA 51-150
    Reactivity
    • 21
    • 17
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 34
    • 1
    Rabbit
    Clonality
    • 34
    • 1
    Polyclonal
    Conjugate
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GCAP1 antibody is un-conjugated
    Application
    • 29
    • 16
    • 12
    • 12
    • 10
    • 5
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Cow,Sheep,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GCAP1
    Isotype
    IgG
    Top Product
    Discover our top product GUCA1A Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    GCAP1 (GUCA1A) (Guanylate Cyclase Activator 1A (Retina) (GUCA1A))
    Alternative Name
    GCAP1 (GUCA1A Products)
    Synonyms
    C6orf131 antibody, COD3 antibody, CORD14 antibody, GCAP antibody, GCAP1 antibody, GUCA antibody, GUCA1 antibody, dJ139D8.6 antibody, MGC84170 antibody, GUCA1A antibody, guca1a antibody, MGC146317 antibody, GC-A antibody, Gcap1 antibody, Guca1 antibody, mGCAP1 antibody, gcap1 antibody, guanylate cyclase activator 1A antibody, guanylate cyclase activator 1A L homeolog antibody, guanylate cyclase activator 1A (retina) antibody, guanylate cyclase activator 1a (retina) antibody, GUCA1A antibody, Guca1a antibody, guca1a.L antibody, guca1a antibody
    Background

    Synonyms: COD3, GCAP 1, GCAP, Guanylate Cyclase Activating Protein Photoreceptor 1, Guanylate Cyclase Activating Protein Photoreceptor 1, Guanylate Cyclase Activator 1A, Guanylate Cyclase Activator 1A, Guanylin 1, Guanylin 1, guanylyl cyclase activating protein 1, Guanylyl cyclase-activating protein 1, GUC1A_HUMAN, GUCA, GUCA1, GUCA1A, GUCA1A.

    Background: intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating protein (GCAP1). GCAPs are calcium-The binding proteins belonging to the calmodulin superfamily. GCAP1 is a calcium-binding protein that stimulates synthesis of c-GMP in photoreceptors. GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs. In contrast to other calcium-binding proteins from the calmodulin superfamily, the calcium-free form of GCAP1 stimulates the effector enzyme. By molecular cloning of human and mouse GCAP cDNA, the known mammalian GCAPs are found to be more than 90 % similar, consisting of 201 to 205 amino acids, and containing three identically conserved calcium-binding sites. A related protein, GCAP2, is detectable only in the retina and results from a gene duplication event.

    Gene ID
    2978
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
You are here:
Support