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Claudin 6/9 antibody

Reactivity: Human cELISA, FACS Host: Rat Monoclonal YD-9H8 unconjugated
Catalog No. ABIN1720918
  • Target
    Claudin 6/9
    Reactivity
    Human
    Host
    Rat
    Clonality
    Monoclonal
    Application
    Cell-ELISA (cELISA), Flow Cytometry (FACS)
    Specificity
    Anti-human Claudin 6 and Claudin 9
    Characteristics
    Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    Purification
    Protein G
    Immunogen
    genetic immunisation with cDNA encoding human Claudin 9
    Clone
    YD-9H8
    Isotype
    IgG2b
  • Application Notes
    Flow cytometry: 1.2 µg/10^6 cells
    ELISA: 1:200 - 1:400
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    Comment

    Synonyms: CLDN6, CLDN9

    Restrictions
    For Research Use only
  • Buffer
    PBS, pH 7.2
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C
    Storage Comment
    short term: 2 °C - 8 °C, long term: -20 °C
  • Fofana, Zona, Thumann, Heydmann, Durand, Lupberger, Blum, Pessaux, Gondeau, Reynolds, McKeating, Grunert, Thompson, Zeisel, Baumert: "Functional analysis of claudin-6 and claudin-9 as entry factors for hepatitis C virus infection of human hepatocytes by using monoclonal antibodies." in: Journal of virology, Vol. 87, Issue 18, pp. 10405-10, (2013) (PubMed).

  • Target
    Claudin 6/9
    Background
    Claudin 6 and 9 play a major role in tight junction-specific obliteration of the intercellular space. Claudin 6 and Claudin 9 have been reported to mediate HCV entry
    UniProt
    P19235, O95484
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