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NMDAR3A + 3B antibody
GRIN3A/B
Reactivity: Human, Mouse, Rat
IP, WB, IHC
Host: Mouse
Monoclonal
K35-40
unconjugated
Product Details anti-NMDAR3A + 3B Antibody
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Target
See all NMDAR3A + 3B (GRIN3A/B) products
NMDAR3A + 3B (GRIN3A/B)
(Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 3A/B (GRIN3A/B))
Reactivity
Human, Mouse, Rat
Host
All hosts for NMDAR3A + 3B antibodies
Mouse
Clonality
All clonalities for NMDAR3A + 3B antibodies
Monoclonal
Conjugate
All conjugates for NMDAR3A + 3B antibodies
This NMDAR3A + 3B antibody is un-conjugated
Application
Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (IHC)
Specificity
Reacts with human Glutamate NMDA Receptor NR3A/B Subunit. Cross-reacts with mouse and rat protein. Do not cross-react with subunits NR1 or NR2A-D.
Purification
Purified (protein G)
Immunogen
Fusion protein of NR3A aa sequence 780-914 from the extracellular IIIIV loop.
Clone
K35-40
Isotype
IgG1
Alternatives
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Application Details
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Application Notes
Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only : IHC(1 - 10 μg/mL) WB (1 - 10 μg/mL)
Restrictions
For Research Use only
Handling
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Buffer
PBS, pH 7.4.
Handling Advice
Dilute in PBS or medium that is identical to that used in the assay system.
Storage
-20 °C
Storage Comment
Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
Expiry Date
12 months
Target Details for NMDAR3A + 3B
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Target
NMDAR3A + 3B (GRIN3A/B)
(Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 3A/B (GRIN3A/B))
Abstract
GRIN3A/B Products
Background
Two new subunits of the NMDA subtype of glutamate receptor (NMDAR) have been identified, NR3A and NR3B, with NR3B likely being the final member of the NMDAR family. These subunits show high sequence homology, although different distribution patterns: NR3B is expressed predominately in motor neurons, while NR3A is more widely distributed. When expressed in Xenopus oocytes, NR3A or NR3B assemble with NR1 to form excitatory glycine receptors that are unaffected by glutatmate. Glutamate receptor ionotropic, NMDA 3A, GluN3A N-methyl-D-aspartate receptor subtype 3A, NMDAR3A, NR3A NMDAR-L
Gene ID
116443
UniProt
Q8TCU5
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