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CCL2 antibody

CCL2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1A7B8 unconjugated
Catalog No. ABIN1724636
  • Target See all CCL2 Antibodies
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    Reactivity
    • 96
    • 61
    • 57
    • 18
    • 18
    • 18
    • 16
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 116
    • 54
    • 8
    • 7
    • 3
    • 2
    • 2
    Mouse
    Clonality
    • 132
    • 60
    Monoclonal
    Conjugate
    • 105
    • 33
    • 14
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CCL2 antibody is un-conjugated
    Application
    • 136
    • 67
    • 56
    • 27
    • 26
    • 25
    • 24
    • 18
    • 15
    • 13
    • 13
    • 12
    • 12
    • 11
    • 11
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human MCP-1 expressed in E. coli.
    Clone
    1A7B8
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CCL2 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    Alternative Name
    MCP-1 (CCL2 Products)
    Synonyms
    GDCF-2 antibody, HC11 antibody, HSMCR30 antibody, MCAF antibody, MCP-1 antibody, MCP1 antibody, SCYA2 antibody, SMC-CF antibody, AI323594 antibody, JE antibody, Scya2 antibody, Sigje antibody, MCP-1A antibody, MCP1A antibody, C-C motif chemokine ligand 2 antibody, chemokine (C-C motif) ligand 2 antibody, C-C motif chemokine 2 antibody, CCL2 antibody, Ccl2 antibody, LOC101120093 antibody
    Background

    Description: Monocyte chemoattractant protein-1 (MCP-1) is a member of the chemokine-beta family of cytokines. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. It may play a inprotant role in the initiation and/or progression of pulmonary hypertension (PH). Blockade of a systemic MCP-1 signal pathway in vivo may prevent PH.

    Aliases: MCP1

    Gene ID
    6347
    HGNC
    6347
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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