ADAMTS1 antibody (Internal Region)

Catalog No. ABIN1731523

Product Details anti-ADAMTS1 Antibody

Target: ADAMTS1 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAMTS1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with human ADAMTS1

Cross-Reactivity (Details): BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ADAMTS8 (61 % ).

Purification: Antigen affinity purified

Immunogen: Synthetic 18 amino acid peptide from internal region of human ADAMTS1. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Orangutan (100%), Gibbon (100%), Monkey (100%), Marmoset (100%), Rabbit (100%), Horse (100%)

Isotype: IgG

Application Details

Application Notes:

Working dilution: IHC - P (1.3 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.

Target Details for ADAMTS1

Target: ADAMTS1 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1))

Alternative Name: ADAMTS1 (ADAMTS1 Products)

Synonyms: c3-c5 antibody, meth1 antibody, xadamts1 antibody, C3-C5 antibody, METH1 antibody, ADAM-TS1 antibody, ADAMTS antibody, ADAMTS-1 antibody, METH-1 antibody, adamts1 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 1 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 1 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 1 L homeolog antibody, ADAMTS1 antibody, adamts1 antibody, Adamts1 antibody, adamts1.L antibody

Background: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.

UniProt: Q9UHI8

Pathways: SARS-CoV-2 Protein Interactome