P2RX7 antibody (C-Term)
-
- Target See all P2RX7 Antibodies
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
-
Binding Specificity
- AA 363-595, C-Term
-
Reactivity
- Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This P2RX7 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Specificity
- Specific for P2X7.
- Purification
- Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.
- Immunogen
- Recombinant cytoplasmic C-terminal tail of mouse P2X7 (aa 363-595).
- Top Product
- Discover our top product P2RX7 Primary Antibody
-
-
- Application Notes
-
WB: 1 : 1000 (AP staining)
IP: not tested yet
ICC: not tested yet
IHC: not tested yet - Comment
-
Detects mouse protein with higher sensitivity. This antibody detects an additional band at 30 kDa of unknown identity.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
- Buffer
- PBS
- Handling Advice
- Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.
- Storage
- -20 °C
- Storage Comment
- Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!
-
-
A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90." in: Autophagy, Vol. 11, Issue 1, pp. 113-30, (2015) (PubMed).
: "P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatment." in: Journal of cellular and molecular medicine, Vol. 16, Issue 5, pp. 1026-37, (2012) (PubMed).
: "Expression, assembly and function of novel C-terminal truncated variants of the mouse P2X7 receptor: re-evaluation of P2X7 knockouts." in: British journal of pharmacology, Vol. 165, Issue 4, pp. 978-93, (2012) (PubMed).
: "
-
A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90." in: Autophagy, Vol. 11, Issue 1, pp. 113-30, (2015) (PubMed).
-
- Target
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
- Alternative Name
- P2X7 (P2RX7 Products)
- Synonyms
- p2xr7 antibody, P2RX7 antibody, P2X7 antibody, AI467586 antibody, P2X(7) antibody, P2X7R antibody, p2x7 antibody, purinergic receptor P2X 7 antibody, purinergic receptor P2X, ligand-gated ion channel, 7 antibody, P2X purinoceptor 7 antibody, P2RX7 antibody, p2rx7 antibody, LOC100458463 antibody, P2rx7 antibody
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
-