Deltex Homolog 3 antibody (AA 19-30)

Catalog No. ABIN1804727

Product Details anti-Deltex Homolog 3 Antibody

Target: Deltex Homolog 3 (DTX3) (Deltex Homolog 3 (Drosophila) (DTX3))

Binding Specificity: AA 19-30

Reactivity: Human, Mouse, Cow, Rat, Horse, Pig, Rabbit, Monkey, Hamster

Host: Goat

Clonality: Polyclonal

Conjugate: This Deltex Homolog 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human DTX3.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-KNKVTVSKPVWD from an internal region (near N-terminus) of human DTX3 (NP_848597.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Horse, Rabbit, Pig (100%), Bat (92%), Xenopus (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (10 μg/mL), Peptide-ELISA, WB (0.2 - 0.5 μg/mL)

Usage: Western Blot: Approx 90kD band observed in Mouse Fetal Brain lysates and in lysates of cell line NIH3T3 (calculated MW of 38.0kD according to Human NP_848597.1 and 37.98kD to Mouse NP_109639.1). The observed much higher molecular weight corresponds to earlier findings in literature with different antibodies (Takeyama et al, J Biol Chem. 2003 Jun13,278(24):21930-7., PMID: 12670957). Recommended concentration: 0.2-0.5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Deltex Homolog 3

Target: Deltex Homolog 3 (DTX3) (Deltex Homolog 3 (Drosophila) (DTX3))

Alternative Name: DTX3 (DTX3 Products)

Synonyms: RGD1566181 antibody, Deltex3 antibody, mg310 antibody, RNF154 antibody, deltex E3 ubiquitin ligase 3 antibody, deltex homolog 3 (Drosophila) antibody, deltex 3, E3 ubiquitin ligase antibody, Dtx3 antibody, DTX3 antibody, dtx3 antibody

Background: Name/Gene ID: DTX3

Synonyms: DTX3, Deltex homolog 3 (Drosophila), Deltex 3 homolog (Drosophila), RNF154, Deltex 3 homolog, Deltex3, Protein deltex-3, RING finger protein 154

Gene ID: 196403

NCBI Accession: NP_848597

UniProt: Q8N9I9

Pathways: Notch Signaling