Caspase 8 antibody (AA 180-480)

Catalog No. ABIN1818448

This Mouse Monoclonal antibody specifically detects Caspase 8 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for Caspase 8 antibody (AA 180-480) (ABIN1818448)

Target: Caspase 8 (CASP8)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Caspase 8 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 5D3

Product Details anti-Caspase 8 Antibody

Binding Specificity: AA 180-480

Specificity: Human caspase 8

Purification: Protein A purified

Immunogen: Recombinant Human Caspase-8 (C-terminal 180-480 a. a.).

Type of Immunogen: Recombinant protein

Isotype: IgG2b kappa

Application Details

Application Notes: Approved: IP, WB (1 μg/mL)

Usage: IP: 1 μg/200 μL of cell extract from 2.5x10⁶ cells,

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 50 % glycerol

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: CASP8 / Caspase 8

Background: Name/Gene ID: CASP8
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP8, ALPS2B, Apoptotic protease Mch-5, Apoptotic cysteine protease, Casp-8, Caspase-8, CAP4, Caspase 8, MACH, MCH5, MORT1-associated ced-3 homolog, ICE-like apoptotic protease 5, Pro Caspase 8, FADD-like ICE, FLICE, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein

Gene ID: 841

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades