IL22 Receptor alpha 1 antibody (AA 42-70)

Catalog No. ABIN1819423

Product Details anti-IL22 Receptor alpha 1 Antibody

Target: IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))

Binding Specificity: AA 42-70

Reactivity: Human, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This IL22 Receptor alpha 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Recognizes an epitope within the N-terminal (NT) region of human interleukin-22 receptor (IL-22R), also known as IL-22R alpha-1 (IL22RA1), a member of the type II cytokine receptor family, which signals via the JAK-STAT signalling pathway. IL-22R acts as the functional receptor for IL-22, through association with the beta chain of the IL-10R, and as a receptor for IL-20 and IL-24 through association with the beta chain of IL-20R. Binding of IL-22 to functional IL-22R can be blocked by a soluble form of the receptor known as IL22 binding protein (IL22BP).

Purification: Affinity purified

Immunogen: Synthetic peptide DSGPEGTPDTVYSIEYKTYGERDWVAKKG corresponding to amino acids 42-70 within the N-terminal region of human IL-22 receptor. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Monkey (100%), Gibbon, Marmoset (93%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (1:50000), IF (1:100), IHC, IHC-P (1:150)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for IL22 Receptor alpha 1

Target: IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))

Alternative Name: IL22RA1 / IL22R (IL22RA1 Products)

Synonyms: IL22RA1 antibody, CRF2-9 antibody, IL22R antibody, IL22R1 antibody, 9130219A07Rik antibody, ENSMUSG00000073746 antibody, IL-22R antibody, Il22r antibody, RGD1559655 antibody, interleukin 22 receptor subunit alpha 1 antibody, interleukin 22 receptor, alpha 1 antibody, IL22RA1 antibody, Il22ra1 antibody

Background: Name/Gene ID: IL22RA1
Family: Interleukin

Synonyms: IL22RA1, CRF2-9, IL-22RA1, IL-22 receptor subunit alpha-1, IL22R, IL-22R-alpha-1, ZcytoR11, IL22R1, Interleukin 22 receptor

Gene ID: 58985

UniProt: Q8N6P7