MMP1 antibody (C-Term)
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- Target See all MMP1 Antibodies
- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MMP1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- Recognizes human matrix metalloproteinase 1 (MMP-1). The MMPs are zinc-dependent endopeptidases responsible for degrading the extracellular matrix. They are also involved in cell proliferation, migration, differentiation and apoptosis. Most MMPs are synthesized as inactive zymogens and a propeptide region must be cleaved off before the enzyme becomes active. Their expression is increased dramatically in a variety of cancer types, where it indicates invasive disease and a poor prognosis. MMP-1 is one of the collagenases, capable of degrading collagens I, II and III, all main components of the interstitial stroma. It is overexpressed in invasive melanoma, colorectal and esophageal cancers. It has also been implicated in arthritis and might influence atherosclerotic lesion formation. It might also be involved in the repair processes of the heart after myocardial infarction.
- Purification
- Protein G purified
- Immunogen
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Ovalbumin conjugated synthetic peptide corresponding to a region within the C-terminus of human MMP-1.
Type of Immunogen: Synthetic peptide - Clone
- 3B6
- Isotype
- IgG1
- Top Product
- Discover our top product MMP1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
- Alternative Name
- MMP1 (MMP1 Products)
- Synonyms
- CLG antibody, CLGN antibody, Mmp1a antibody, CG4859 antibody, Dm1-MMP antibody, Dmel\\CG4859 antibody, MMP-1 antibody, MMP1 antibody, Mmp 1 antibody, dMMP1 antibody, dm1-MMP antibody, dmmp1 antibody, l(2)k04809 antibody, mmp1 antibody, Mmp1 antibody, Mcol-A antibody, Mcola antibody, col4 antibody, mmp18 antibody, Clgn antibody, matrix metallopeptidase 1 antibody, Matrix metalloproteinase 1 antibody, matrix metalloproteinase 1 antibody, matrix metallopeptidase 1 (interstitial collagenase) antibody, matrix metallopeptidase 1a (interstitial collagenase) antibody, matrix metallopeptidase 1 S homeolog antibody, interstitial collagenase antibody, matrix metallopeptidase 8 L homeolog antibody, MMP1 antibody, Mmp1 antibody, RB11133 antibody, Mmp1a antibody, mmp1.S antibody, LOC100727966 antibody, mmp8.L antibody
- Background
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Name/Gene ID: MMP1
Subfamily: Metallopeptidase M10A
Family: Protease
Synonyms: MMP1, CLG, Fibroblast collagenase, Matrix metalloprotease 1, MMP-1, Interstitial collagenase, Matrix metalloproteinase 1, Matrix metalloproteinase-1 - Gene ID
- 4312
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