CD52 antibody

Catalog No. ABIN1819975

Product Details anti-CD52 Antibody

Target: CD52

Reactivity: Human, Monkey, Cynomolgus

Host: Rat

Clonality: Monoclonal

Conjugate: This CD52 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Cytotoxicity Test (CyTox)

Specificity: Reacts with the human CD52 antigen, also known as CAMPATH-1. The CD52 antigen is a remarkably small peptide that is heavily glycosylated, and attached to the cell surface membrane via a GPI link. The apparent molecular mass of the antigen on SDS-PAGE is 25-29kD. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable. Humanized versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies.

Purification: Ammonium sulfate precipitation

Immunogen: Human T lymphocytes.

Type of Immunogen: Cells

Clone: YTH66-9HL

Isotype: IgM

Application Details

Application Notes: Approved: Ctox, Flo (1:20), IHC, IHC-Fr (1:20), WB

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for CD52

Target: CD52

Alternative Name: CD52 (CD52 Products)

Synonyms: CD52 antibody, AI463198 antibody, B7 antibody, B7-Ag antibody, CAMPATH-1 antibody, CLS1 antibody, MB7 antibody, CDW52 antibody, CE5 antibody, CD52 molecule antibody, CD52 antigen antibody, CD52 antibody, Cd52 antibody

Background: Name/Gene ID: CD52

Synonyms: CD52, Cambridge pathology 1 antigen, CD52 antigen, CD52 Molecule, CDW52, CAMPATH-1 antigen, He5

Gene ID: 1043