Caspase 8 antibody

Catalog No. ABIN1821142

This Rat Monoclonal antibody specifically detects Caspase 8 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Caspase 8 antibody (ABIN1821142)

Target: Caspase 8 (CASP8)

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This Caspase 8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: G1-G1-4

Product Details anti-Caspase 8 Antibody

Specificity: Human Caspase-8.

Purification: Affinity purified

Immunogen: Full length caspase-8 fusion protein.

Type of Immunogen: Fusion protein

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: CASP8 / Caspase 8

Background: Name/Gene ID: CASP8
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP8, ALPS2B, Apoptotic protease Mch-5, Apoptotic cysteine protease, Casp-8, Caspase-8, CAP4, Caspase 8, MACH, MCH5, MORT1-associated ced-3 homolog, ICE-like apoptotic protease 5, Pro Caspase 8, FADD-like ICE, FLICE, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein

Gene ID: 841

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades