NLRP3 antibody (AA 4-223)

Catalog No. ABIN1821302

The Mouse Monoclonal anti-NLRP3 antibody has been validated for ICC. It is suitable to detect NLRP3 in samples from Human.

Quick Overview for NLRP3 antibody (AA 4-223) (ABIN1821302)

Target: NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NLRP3 antibody is un-conjugated

Application: Immunocytochemistry (ICC)

Clone: 1D4B

Product Details anti-NLRP3 Antibody

Binding Specificity: AA 4-223

Specificity: Human NALP3. Does not react with recombinant human NALP1, 2, 5, rhNALP3 aa540-689, or recombinant mouse NALP3.

Purification: Affinity purified

Immunogen: Recombinant corresponding to aa4-223 from human NALP3 expressed in E.coli.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: ICC (8 - 25 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile PBS to 0.5 mg/mL.

Concentration: Lot specific

Buffer: Lyophilized from PBS, trehalose

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.

Target Details for NLRP3

Target: NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

Alternative Name: NALP3 / NLRP3

Background: Name/Gene ID: NLRP3

Synonyms: NLRP3, AGTAVPRL, AII, C1orf7, Caterpiller protein 1.1, Cryopyrin, FCAS, FCU, PYPAF1, NALP3, CIAS1, CLR1.1, MWS

Gene ID: 114548

UniProt: Q96P20

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome