Bcl-2 antibody (AA 2-211)
Quick Overview for Bcl-2 antibody (AA 2-211) (ABIN1823063)
Target
See all Bcl-2 (BCL2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 2-211
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Specificity
- Human Bcl-2. Species sequence homology: recombinant mouse Bcl-2 (25-40 % ), rmBcl-2. Does not react with recombinant human BCL2L12.
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Purification
- Affinity purified
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Immunogen
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Recombinant corresponding to aa2-211 from human Bcl-1 expressed in E. coli (P10415).
Type of Immunogen: Recombinant protein -
Isotype
- IgG2b
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Application Notes
- Approved: IHC (8 - 25 μg/mL), WB (0.1 μg/mL)
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Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Sterile PBS to 0.5 mg/mL.
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS, trehalose
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Handling Advice
- Aliquot to avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Alternative Name
- BCL2 / Bcl-2
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Background
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Name/Gene ID: BCL2
Family: Apoptosis
Synonyms: BCL2, Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, B-cell lymphoma protein 2, Bcl-2, PPP1R50 -
Gene ID
- 596
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UniProt
- P10415
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Pathways
- MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Target
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