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Lysine (K)-Specific Methyltransferase 2B (KMT2B) (N-Term) antibody

Verified KMT2B Reactivity: Human ELISA, IHC Host: Goat Polyclonal unconjugated
Catalog No. ABIN184880
$448.50
Plus shipping costs $45.00
100 μg
Shipping to: United States
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  • Target See all Lysine (K)-Specific Methyltransferase 2B (KMT2B) Antibodies
    Lysine (K)-Specific Methyltransferase 2B (KMT2B)
    Binding Specificity
    • 4
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 17
    • 8
    • 1
    Human
    Host
    • 15
    • 2
    Goat
    Clonality
    • 15
    • 2
    Polyclonal
    Conjugate
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    ELISA, Immunohistochemistry (IHC)
    Purpose
    KMT2D/MLL2
    Sequence
    DSQNLAGEDK DSQ
    Specificity
    The immunizing peptide was designed from NP_003473.1. Since then the sequence has changed in the databases and currently differs at two locations in NP_003473.3.
    Predicted Reactivity
    Human
    Purification
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Grade
    Verified
    Immunogen
    Peptide with sequence DSQNLAGEDKDSQ-C, from the N Terminus of the protein sequence according to NP_003473.3.
    Isotype
    IgG
  • Application Notes

    DS WB Results: Using our routine western blotting protocol we would not expect to reliably detect proteins larger than 250 kDa (calculated MW of approx. 593KDa according to NP_003473.3).

    DS IHC Results: In paraffin embedded Human Placenta shows nuclear stainng in the trophoblasts . Similar nuclear patches are observed in Human Liver. Recommended concentration: 4-8 μg/mL.

    Peptide ELISA: antibody detection limit dilution 1:16000.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Minimize freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Target
    Lysine (K)-Specific Methyltransferase 2B (KMT2B)
    Alternative Name
    KMT2D (KMT2B Products)
    Synonyms
    HRX2 antibody, MLL1B antibody, MLL2 antibody, MLL4 antibody, TRX2 antibody, WBP7 antibody, lysine methyltransferase 2B antibody, KMT2B antibody
    Background
    MLL2, myeloid/lymphoid or mixed-lineage leukemia 2, ALR, ALL1-related gene, AAD10, CAGL114, KMT2D, MLL4, TNRC21, ALL1-related, trinucleotide repeat containing 21, KMS, KABUK1, Lysine methyltransferase 2D
    Gene ID
    8085
    NCBI Accession
    NP_003473
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