HIST1H3/2H3/3H3/H3F3 (AA 28-57), (N-Term) antibody
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- Target
- HIST1H3/2H3/3H3/H3F3
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Binding Specificity
- AA 28-57, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
- Application
- Western Blotting (WB)
- Predicted Reactivity
- B, M, Rat, C, Zf, X, E, D, Pig, Rb
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This HIST1H3/2H3/3H3/H3F3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-57 amino acids from the N-terminal region of human HIST1H3/2H3/3H3/H3F3.
- Clone
- RB42493
- Isotype
- Ig Fraction
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- Application Notes
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- HIST1H3/2H3/3H3/H3F3
- Background
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
- Molecular Weight
- 15404
- NCBI Accession
- NP_003520, NP_003521, NP_003522, NP_003523, NP_003524, NP_003525, NP_003526, NP_003527, NP_003528, NP_066298
- UniProt
- P68431
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