This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This NDUFS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-146 amino acids from the Central region of human NDUFS7.
NDUFS7
Reactivity: Human, Mouse, Rat
ELISA, IHC, WB, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
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Grimwood, Gordon, Olsen, Terry, Schmutz, Lamerdin, Hellsten, Goodstein, Couronne, Tran-Gyamfi, Aerts, Altherr, Ashworth, Bajorek, Black, Branscomb, Caenepeel, Carrano, Caoile, Chan, Christensen et al.: "The DNA sequence and biology of human chromosome 19. ..." in: Nature, Vol. 428, Issue 6982, pp. 529-35, (2004) (PubMed).
Murray, Zhang, Taylor, Oglesbee, Fahy, Marusich, Ghosh, Capaldi: "The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification." in: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 13619-22, (2003) (PubMed).
Triepels, van den Heuvel, Loeffen, Buskens, Smeets, Rubio Gozalbo, Budde, Mariman, Wijburg, Barth, Trijbels, Smeitink: "Leigh syndrome associated with a mutation in the NDUFS7 (PSST) nuclear encoded subunit of complex I." in: Annals of neurology, Vol. 45, Issue 6, pp. 787-90, (1999) (PubMed).
Hyslop, Duncan, Pitkänen, Robinson: "Assignment of the PSST subunit gene of human mitochondrial complex I to chromosome 19p13." in: Genomics, Vol. 37, Issue 3, pp. 375-80, (1997) (PubMed).
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).