This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SSX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SSX7.
SSX7
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
APC
Application Notes
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Güre, Wei, Old, Chen: "The SSX gene family: characterization of 9 complete genes." in: International journal of cancer. Journal international du cancer, Vol. 101, Issue 5, pp. 448-53, (2002) (PubMed).
Chen, Chen, Lee, Huang, Yang, Tsai, Chen, Sheu: "Expressions of cancer-testis antigens in human hepatocellular carcinomas." in: Cancer letters, Vol. 164, Issue 2, pp. 189-95, (2001) (PubMed).
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation.