UBE2L3 antibody (Ubiquitin-Conjugating Enzyme E2L 3) (AA 123-153)

Details for Product anti-UBE2L3 Antibody No. ABIN1882145, Supplier: Log in to see
Antigen
  • E2-F1
  • L-UBC
  • UBCH7
  • UbcM4
  • C79827
  • Ubce7
  • ube2l3
  • wu:fc22h11
  • zgc:86727
  • UBE2L3
  • ube2l3l
  • wu:fb38h03
  • ubiquitin conjugating enzyme E2 L3
  • ubiquitin-conjugating enzyme E2L 3
  • ubiquitin-conjugating enzyme E2L 3a
  • ubiquitin conjugating enzyme E2 L3 S homeolog
  • ubiquitin-conjugating enzyme E2L 3b
  • UBE2L3
  • Ube2l3
  • ube2l3a
  • ube2l3.S
  • ube2l3b
Epitope
AA 123-153, C-Term
40
18
10
10
7
3
2
2
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
124
59
54
11
11
7
7
7
6
6
6
6
4
4
2
Host
Rabbit
101
19
5
Clonality (Clone)
Polyclonal ()
Conjugate
This UBE2L3 antibody is un-conjugated
7
7
7
5
5
5
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
105
58
43
24
13
12
8
6
4
2
1
Options
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Immunogen This UBE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L3.
Clone RB4154
Predicted Reactivity Cow (Bovine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)
Plasmids, Primers & others Plasmids, Primers & others UBE2L3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name UBE2L3 (UBE2L3 Antibody Abstract)
Background The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.

Synonyms: UBE2L3, UBCE7, UBCH7, Ubiquitin-conjugating enzyme E2 L3, L-UBC, UbcH7, Ubiquitin carrier protein L3, Ubiquitin-conjugating enzyme E2-F1, Ubiquitin-protein ligase L3
NCBI Accession NP_003338, NP_001243284, NP_001243285
UniProt P68036
Application Notes WB: 1:1000,IHC (p): 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Immunohistochemistry (IHC) image for anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (AA 123-153), (C-Term) antibody (ABIN1882145) UBE2L3 Antibody (C-term) (ABIN1882145) western blot analysis in U87-MG,mouse NIH/3T3,...
Western Blotting (WB) image for anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (AA 123-153), (C-Term) antibody (ABIN1882145) UBE2L3 Antibody (C-term) (ABIN1882145) western blot analysis in U87-MG,mouse NIH/3T3,...
Product cited in: Moynihan, Cole, Dunham, ONeil, Markham, Robinson: "Fine-mapping, genomic organization, and transcript analysis of the human ubiquitin-conjugating enzyme gene UBE2L3." in: Genomics, Vol. 51, Issue 1, pp. 124-7, 1998 (PubMed).

Moynihan, Ardley, Leek, Thompson, Brindle, Markham, Robinson: "Characterization of a human ubiquitin-conjugating enzyme gene UBE2L3." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 7, Issue 7, pp. 520-5, 1996 (PubMed).

Nuber, Schwarz, Kaiser, Schneider, Scheffner: "Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5." in: The Journal of biological chemistry, Vol. 271, Issue 5, pp. 2795-800, 1996 (PubMed).

Robinson, Leek, Thompson, Carr, Bailey, Moynihan, Coletta, Lench, Markham: "A human ubiquitin conjugating enzyme, L-UBC, maps in the Alzheimer's disease locus on chromosome 14q24.3." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 6, Issue 10, pp. 725-31, 1996 (PubMed).

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