RPA 14 kDa Subunit (AA 1-91) antibody
Reactivity: Human
IHC, WB
Host: Rabbit
Polyclonal
unconjugated
-
- Target
- RPA 14 kDa Subunit
- Binding Specificity
- AA 1-91
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Immunohistochemistry (IHC), Western Blotting (WB)
- Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 91 of RPA 14 kDa subunit
-
- Application Notes
-
Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- 1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- Biohazard Informations: This product contains thimerosal which is hazardous.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
- Target
- RPA 14 kDa Subunit
- Background
-
Required for DNA recombination, repair and replication.The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.Functions as component of the alternative replication protein A complex (aRPA).aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S-phase.In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
- Gene ID
- 6119
- NCBI Accession
- NM_002947, NP_002938
-
You are here:
