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GAD antibody (AA 280-582)
GAD1
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GAD Antibody
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Target
See all GAD (GAD1) Antibodies
GAD (GAD1)
(Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
Binding Specificity
All epitopes for GAD antibodies
AA 280-582
Reactivity
All reactivities for GAD antibodies
Human
Host
All hosts for GAD antibodies
Rabbit
Clonality
All clonalities for GAD antibodies
Polyclonal
Conjugate
All conjugates for GAD antibodies
This GAD antibody is un-conjugated
Application
All applications for GAD antibodies
Western Blotting (WB), Immunofluorescence (IF)
Purification
Purified by antigen-affinity chromatography.
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 280 and 582 of GAD1
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Discover our top product GAD1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
1 x PBS, 40 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for GAD
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Target
GAD (GAD1)
(Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
Alternative Name
GAD67 (GAD1 Products )
Synonyms
CPSQ1 antibody, GAD antibody, SCP antibody, GAD-67 antibody, cpsq1 antibody, gad1 antibody, gad1-A antibody, gad67 antibody, GAD67 antibody, GAD1 antibody, GLUTAMATE DECARBOXYLASE antibody, GLUTAMATE DECARBOXYLASE 1 antibody, MKP11.30 antibody, MKP11_30 antibody, glutamate decarboxylase antibody, EP10 antibody, GAD25 antibody, GAD44 antibody, Gad-1 antibody, Gad67 antibody, glutamate decarboxylase 1 antibody, glutamate decarboxylase 1 L homeolog antibody, glutamate decarboxylase antibody, glutamate decarboxylase 1b antibody, GAD1 antibody, gad1.1.L antibody, GAD antibody, Gad1 antibody, gad1b antibody
Background
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes.The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid.A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes.This gene may also play a role in the stiff man syndrome.Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures.Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.[provided by RefSeq]
Molecular Weight
67 kDa
Gene ID
2571
NCBI Accession
NP_000808 , NM_000817
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