RASSF1 antibody (AA 50-334)

Catalog No. ABIN1886518

This Rabbit Polyclonal antibody specifically detects RASSF1 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for RASSF1 antibody (AA 50-334) (ABIN1886518)

Target: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASSF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-RASSF1 Antibody

Binding Specificity: AA 50-334

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 50 and 334 of RASSF1

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for RASSF1

Target: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Alternative Name: RASSF1

Background: This gene encodes a protein similar to the RAS effector proteins.Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene.The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region.The encoded protein was found to interact with DNA repair protein XPA.The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest.Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.[provided by RefSeq]

Molecular Weight: 39 kDa

Gene ID: 11186

NCBI Accession: NP_733832, NM_170714