PSMC3 antibody (AA 51-331)
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- Target See all PSMC3 Antibodies
- PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))
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Binding Specificity
- AA 51-331
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMC3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 51 and 331 of PSMC3
- Top Product
- Discover our top product PSMC3 Primary Antibody
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- Application Notes
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- Biohazard Informations: This product contains thimerosal which is hazardous.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Target
- PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))
- Alternative Name
- PSMC3 (PSMC3 Products)
- Synonyms
- TBP1 antibody, TBP-1 antibody, wu:fb39a02 antibody, zgc:86713 antibody, psmc3 antibody, MGC89608 antibody, PSMC3 antibody, NV15940 antibody, 23.m06430 antibody, DDBDRAFT_0186002 antibody, DDBDRAFT_0232967 antibody, DDB_0186002 antibody, DDB_0232967 antibody, psmc3-b antibody, tbp10 antibody, psmc3-a antibody, proteasome 26S subunit, ATPase 3 antibody, proteasome (prosome, macropain) 26S subunit, ATPase 3 antibody, 26S protease regulatory subunit 6A antibody, 26S protease regulatory subunit 6a antibody, 26S protease regulatory subunit 6A-B antibody, 26S protease regulatory subunit 6A, putative antibody, proteasome 26S subunit, ATPase 3 S homeolog antibody, nth-like DNA glycosylase 1 S homeolog antibody, PSMC3 antibody, Psmc3 antibody, HCAG_00069 antibody, GL50803_4365 antibody, EDI_316920 antibody, CpipJ_CPIJ006888 antibody, CpipJ_CPIJ006889 antibody, CpipJ_CPIJ010864 antibody, prs6a antibody, psmc3 antibody, LOC100115023 antibody, BBOV_IV004580 antibody, CGB_M2140W antibody, psmC3 antibody, LOC100637883 antibody, psmc3.S antibody, nthl1.S antibody
- Background
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator.The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity.This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex.A pseudogene has been identified on chromosome 9.[provided by RefSeq]
- Molecular Weight
- 49 kDa
- Gene ID
- 5702
- NCBI Accession
- NM_002804, NP_002795
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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