STS antibody (AA 182-195)
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- Target See all STS Antibodies
- STS (Steroid Sulfatase (STS))
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Binding Specificity
- AA 182-195
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This STS antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- Synthetic peptide corresponding to amino acids 182 to 195 of human ASC.
- Top Product
- Discover our top product STS Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Handling Advice
- Avoid freezing and thawing repeatly.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- Target
- STS (Steroid Sulfatase (STS))
- Alternative Name
- ASC (STS Products)
- Synonyms
- 9130417A21Rik antibody, Asc antibody, CARD5 antibody, TMS-1 antibody, TNS1 antibody, masc antibody, ARSC antibody, ARSC1 antibody, ASC antibody, ES antibody, SSDD antibody, XLI antibody, PYD and CARD domain containing antibody, steroid sulfatase antibody, Pycard antibody, STS antibody, Sts antibody
- Background
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Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases.CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-9, and caspase-2.A novel CARD domain containing protein was recently identified in human and mouse and designated ASC and TMS1.Ectopic expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells (3, 4).Overexpression of ASC/TMS1 induced DNA fragmentation.ASC/TMS1 is expressed in a variety of human and mouse tissues.
- Molecular Weight
- 25 kDa
- Pathways
- Steroid Hormone Biosynthesis, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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