MAK10/NAA35 antibody (Center)

Catalog No. ABIN1887521

Product Details anti-MAK10/NAA35 Antibody

Target: MAK10/NAA35 (MAK10) (MAK10 Homolog, Amino-Acid N-Acetyltransferase Subunit (MAK10))

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAK10/NAA35 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the center of human MAK10.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for MAK10/NAA35

Target: MAK10/NAA35 (MAK10) (MAK10 Homolog, Amino-Acid N-Acetyltransferase Subunit (MAK10))

Alternative Name: MAK10 (MAK10 Products)

Synonyms: MAK10 antibody, bA379P1.1 antibody, A330021G12Rik antibody, A330027C19Rik antibody, AI158944 antibody, C030004C14Rik antibody, Mak10 antibody, T4a antibody, mak10 antibody, wu:fb21g10 antibody, zgc:64157 antibody, N(alpha)-acetyltransferase 35, NatC auxiliary subunit antibody, NAA35 antibody, Naa35 antibody, naa35 antibody

Background: The MAK10 gene encodes a 733-amino acid protein with several regions of similarity to T cell receptor alpha-subunit V (variable) regions in yeast.The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species.It is expressed in a variety of tissues in the developing rat embryo but restricted in expression in the adult, remaining detectable only in tissues undergoing continual cell renewal or in cells responding to pathological injury.The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development.This complex functionally co-assembles in mammalian cells to regulate cell proliferation and is essential for embryonic development, at least in part through the regulation of target of rapamycin (TOR) signaling events.At least two isoforms of MAK10 are known to exist.
Synonyms: amino-acid N-acetyltransferase subunit, Embryonic growth-associated protein homolog, EGAP

NCBI Accession: NP_078911