ANKRD27 antibody (Center)

Catalog No. ABIN1887571

Product Details anti-ANKRD27 Antibody

Target: ANKRD27 (Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKRD27 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the center of human VARP.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for ANKRD27

Target: ANKRD27 (Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27))

Alternative Name: VARP (ANKRD27 Products)

Synonyms: VARP antibody, AA408090 antibody, BC016493 antibody, D330003H11Rik antibody, Varp antibody, ankyrin repeat domain 27 antibody, ankyrin repeat domain 27 (VPS9 domain) antibody, ANKRD27 antibody, Ankrd27 antibody

Background: The VPS9 ankyrin repeat protein (VARP) binds to the Rab21, a guanine nucleotide exchange factor that plays an essential role in endocytic trafficking.VARP localizes to early endosomes and is thought to regulate endosome dynamics.VARP also interacts with TI-VAMP/VAMP7, a vesicular SNARE that mediates an exocytic pathway that is crucial to neurite growth.Depletion of VARP by RNA interference impairs neurite growth, suggesting that VARP is a positive regulator of neurite growth.
Synonyms: VPS9 ankyrin repeat protein, Ankyrin repeat domain-containing protein 27, ANKRD27, PP12899

NCBI Accession: NP_115515