MEX3B antibody (Center)

Catalog No. ABIN1887601

Product Details anti-MEX3B Antibody

Target: MEX3B (Mex-3 Homolog B (MEX3B))

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEX3B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: This antibody is specific for RKHD3 and will not recognize the other RKHD3 family of proteins.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide from near the center of human RKHD3.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for MEX3B

Target: MEX3B (Mex-3 Homolog B (MEX3B))

Alternative Name: RKHD3 (MEX3B Products)

Synonyms: RKHD3 antibody, wu:fc13g02 antibody, wu:fj58h02 antibody, zgc:158350 antibody, fam54b antibody, mex-3b antibody, rkhd3 antibody, MEX-3B antibody, RNF195 antibody, 4931439A04Rik antibody, M-04814 antibody, Rkhd3 antibody, mKIAA2009 antibody, mex-3 homolog B (C. elegans) antibody, mex-3 RNA binding family member B antibody, mex-3 RNA binding family member B S homeolog antibody, mex3 RNA binding family member B antibody, MEX3B antibody, mex3b antibody, mex3b.S antibody, Mex3b antibody

Background: Rkhd3, also known as MEX3B is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module.MEX3 proteins, including Rkhd3, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway.These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms.Rkhd3 is thought to act as a mechanism to fine-tune mRNA regulation in early Xenopus development, and with Rkhd4, but not Rkhd1, will co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
Synonyms: RING finger and KH domain-containing protein 3, MEX3B, Ring finger protein 195, RNF195

NCBI Accession: NP_780575