CDIP1 antibody (Center)

Catalog No. ABIN1887614

Product Details anti-CDIP1 Antibody

Target: CDIP1 (LITAF-Like Protein (CDIP1))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the center of human CDIP.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for CDIP1

Target: CDIP1 (LITAF-Like Protein (CDIP1))

Alternative Name: CDIP (CDIP1 Products)

Synonyms: RGD1310686 antibody, MGC165666 antibody, MGC97537 antibody, 2700048O17Rik antibody, 5730403B10Rik antibody, AU018521 antibody, AW742692 antibody, CDIP antibody, C16orf5 antibody, I1 antibody, LITAFL antibody, MGC52765 antibody, MGC127651 antibody, cell death-inducing p53 target 1 antibody, LITAF-like protein antibody, cell death inducing Trp53 target 1 antibody, cell death inducing p53 target 1 antibody, cell death-inducing p53 target 1 L homeolog antibody, Cdip1 antibody, cdip1 antibody, Bm1_00175 antibody, LOC100168843 antibody, CDIP1 antibody, cdip1.L antibody

Background: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers.CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses.Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway.CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy.Multiple isoforms of CDIP are known to exist.
Synonyms: Cell death involved p53-target

NCBI Accession: NP_037531