ZMIZ2 antibody (Center)

Catalog No. ABIN1887674

Product Details anti-ZMIZ2 Antibody

Target: ZMIZ2 (Zinc Finger, MIZ-Type Containing 2 (ZMIZ2))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZMIZ2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Cross-Reactivity (Details): At least four isoforms are known to exist. ZIMP7 antibody is predicted to not cross-react with other PIAS protein family members.

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the center of human ZIMP7.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for ZMIZ2

Target: ZMIZ2 (Zinc Finger, MIZ-Type Containing 2 (ZMIZ2))

Alternative Name: ZIMP7 (ZMIZ2 Products)

Synonyms: MGC86475 antibody, RGD1309256 antibody, zimp7 antibody, hzimp7 antibody, NET27 antibody, TRAFIP20 antibody, ZIMP7 antibody, hZIMP7 antibody, 2410117E06Rik antibody, D11Bwg0280e antibody, R74931 antibody, Zimp7 antibody, zinc finger, MIZ-type containing 2 S homeolog antibody, zinc finger, MIZ-type containing 2 antibody, zinc finger MIZ-type containing 2 antibody, zmiz2.S antibody, ZMIZ2 antibody, zmiz2 antibody, Zmiz2 antibody

Background: ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator.ZIMP7 is expressed most abundantly in testis.The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7.ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription.The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
Synonyms: Zinc finger MIZ-type containing 2, ZMIZ2, TRAFIP20, PIAS-like protein Zimp7

UniProt: Q8NF64